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Collaborative Research & Industry Partnerships

Integrated analytical and preclinical research supporting therapeutic discovery and developments

 

We combine quantitative analytical chemistry, in vivo pharmacology, and disease-relevant experimental models to characterize drug exposure, biological activity, and therapeutic efficacy. Our specialized expertise in bioactive lipids and lipid signaling provides additional capabilities for investigating complex pharmacological mechanisms, endogenous biomarkers, and novel therapeutic targets. From early analytical method development through preclinical proof-of-concept studies, we work with biotechnology and pharmaceutical companies to develop customized research programs addressing specific scientific and therapeutic development challenges.​

Specialized Expertise: Bioactive Lipids & Lipid Signaling

 

Our laboratory has extensive experience investigating bioactive lipids, lipid metabolism, and lipid-mediated signaling pathways in health and disease. We integrate quantitative lipid analysis with molecular and in vivo pharmacology to characterize endogenous lipid mediators, investigate their biological functions, and evaluate therapeutic strategies targeting lipid signaling pathways.​

Research Capabilities

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  1. Bioanalytical Method Development and Transfer

  2. Quantitative Bioanalysis & Biomarker Measurement

  3. Early In Vivo Pharmacology & PK/PD

  4. Preclinical Disease Modeling & Therapeutic Efficacy

  5. Behavioral & Functional Phenotyping

Buczynski Lab @ Virginia Tech School of Neuroscience VT

© Copyright 2026 | Buczynski/Gregus Lab

School of Neuroscience | Virginia Tech

Twitter @BuczynskiGregus

Created using Wix | Updated 9/27/2026

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